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Blood and serum substances for markers of prostate cancer
Author(s) -
Bangma Chris H.,
Verhagen Paul C.M.S.
Publication year - 2000
Publication title -
microscopy research and technique
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.536
H-Index - 118
eISSN - 1097-0029
pISSN - 1059-910X
DOI - 10.1002/1097-0029(20001201)51:5<430::aid-jemt5>3.0.co;2-1
Subject(s) - prostate cancer , medicine , disease , cancer , prostate , prostatic disease , oncology , prostate carcinoma , pca3 , pathology
Serummarkers for prostate carcinoma are widely applied for the purpose of early detection of cancer and the differentiation between benign and malignant disease, for the pre‐treatment staging of detected prostatic cancers, and for the monitoring of prostate cancer after curative or palliative therapies. This review illustrates the limitations of current markers for prostatic disease in blood en serum. It gives an overview of what is known about PSA and its isoforms, hK2, PSMA, and PSCA, and discusses, based on this information, in what direction current research is developing in order to improve these markers. Microsc. Res. Tech. 51:430–435, 2000. © 2000 Wiley‐Liss, Inc.