Premium
Effect of weaning and dietary galactose supplementation on digesta glycoproteins in pigs
Author(s) -
Pestova Marina I,
Clift Rose E,
Vickers R Jason,
Franklin Mark A,
Mathew Alan G
Publication year - 2000
Publication title -
journal of the science of food and agriculture
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 142
eISSN - 1097-0010
pISSN - 0022-5142
DOI - 10.1002/1097-0010(200010)80:13<1918::aid-jsfa731>3.0.co;2-b
Subject(s) - mucin , weaning , glycoprotein , galactose , biology , mucus , food science , biochemistry , chemistry , zoology , ecology
Changes in pig digesta mucin and glycoprotein content at weaning and with the inclusion of galactose in the postweaning diet were studied. Mucus was collected from ileal contents of cannulated pigs pre‐ and postweaning, and glycoproteins were analysed based on staining patterns and size exclusion chromatography. An increased concentration of intestinal mucin in lumen contents was observed in newly weaned pigs compared to the same pigs prior to weaning. Analysis of O‐linked oligosaccharides indicated changes in mucin structure from pre‐ to postweaning. Supplementing the diet with galactose resulted in modification of mucin in postweaned pigs compared to a control diet and may limit microbial degradation of mucin. These data indicate that weaning and the subsequent transition to a grain‐based diet result in changes to digesta mucin and endogenous glycoproteins; and dietary galactose may play a role in the final composition and quantity of these compounds. © 2000 Society of Chemical Industry