Premium
Current role of radiotherapy in the treatment of locally advanced laryngeal carcinomas
Author(s) -
Cortesina Giorgio,
De Stefani Antonella,
Cavalot Andrea,
Albera Roberto,
Rosso Paola,
Bussi Mario
Publication year - 2000
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/1096-9098(200005)74:1<79::aid-jso17>3.0.co;2-q
Subject(s) - medicine , radiation therapy , stage (stratigraphy) , surgery , medical record , carcinoma , retrospective cohort study , laryngeal neoplasm , survival rate , larynx , paleontology , biology
Background and Objectives During the past few years, radiotherapy (RT) has been increasingly used in combination with surgery in the treatment of locally advanced laryngeal carcinomas to improve survival rates in patients with more extensive tumors. Methods This is a retrospective study of a large series of stage III and IV laryngeal carcinomas, and postoperative RT was indicated for some of these cases. We retrospectively reviewed the medical records of 380 patients with stage III and IV tumors, of which 163 (43%) underwent surgery only and 217 (57%) received surgery and postoperative RT. Results The survival rates of patients who underwent surgery and RT were comparable to those of patients who underwent surgery only, but the former group was composed of subjects suffering from negative prognostic factors. Conclusions The indications for combined treatment should be correlated with the prognostic factors to increase the survival rate of patients with stage III and IV laryngeal carcinoma. J. Surg. Oncol. 2000;74:79–82. © 2000 Wiley‐Liss, Inc.