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Integrated treatment in locally advanced carcinoma of the oropharynx
Author(s) -
Lanza Laura,
Rizzi Lucio,
Durso Domenico,
Occhini Antonio,
Benazzo Marco,
Tinelli Carmine
Publication year - 2000
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/1096-9098(200005)74:1<75::aid-jso16>3.0.co;2-x
Subject(s) - medicine , radiation therapy , chemotherapy , incidence (geometry) , surgery , lymph node , stage (stratigraphy) , carcinoma , survival rate , radiology , paleontology , physics , optics , biology
Abstract Background and Objectives Oropharyngeal carcinoma tends to be aggressive and deeply infiltrative of nearby sites, with an high incidence of lymphnode metastases. The last treatment decision generally depends on the stage of the lesion and the patient's general status. Oropharyngeal tumor is generally treated by integrated treatments. Methods We retrospectively studied 115 patients with locally advanced oropharyngeal tumors treated in our institution with combined therapies compare the results in two differents groups of patients (surgery plus radiotherapy and chemotherapy plus radiotherapy). Results The 3‐year overall survival rate in patients who underwent surgery plus radiotherapy was 82% and in those who underwent chemotherapy plus radiotherapy was 49%. Conclusion The results suggest that surgery followed by radiotherapy seems to be the best treatment in the case of locally advanced oropharyngeal tumor. J. Surg. Oncol. 2000;74:75–78. © 2000 Wiley‐Liss, Inc.