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Result of liver resection as treatment for metastases from noncolorectal cancer
Author(s) -
Benevento Angelo,
Boni Luigi,
Frediani Lorenzo,
Ferrari Alberta,
Dionigi Renzo
Publication year - 2000
Publication title -
journal of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.201
H-Index - 111
eISSN - 1096-9098
pISSN - 0022-4790
DOI - 10.1002/1096-9098(200005)74:1<24::aid-jso6>3.0.co;2-v
Subject(s) - medicine , surgery , hepatectomy , blood loss , incidence (geometry) , blood transfusion , colorectal cancer , survival rate , resection , cancer , physics , optics
Background and Objectives While liver resection for metastatic disease from colorectal cancer extends survival in selected patients, the efficacy of hepatectomy for metastases from other malignancies has not been defined. Methods Between 1988 and 1998, 20 hepatic resections were performed in 18 patients (2 underwent a double resection due to recurrence) as treatment of noncolorectal metastases. One‐, 2‐, and 5‐year overall and disease‐related actuarial survival rates were calculated. Results No intraoperative or early postoperative deaths were reported. Seven minor (30%) and 1 major (5%) postoperative complications occurred; mean blood loss was 401 ± 324 ml. In 25% of patients, intra‐ or postoperative blood transfusion was needed. The mean postoperative hospital stay was 13.2 days (range 9–23). The overall actuarial survival rate was 54% at 1 year, 42% at 2 years, and 21% at 5 years (mean 38 ± 11 months). Survival is related to the primary tumor nature. Conclusions Hepatic resection for metastases from noncolorectal carcinoma is safe and feasible, with a relatively low incidence of intra‐ or postoperative complications and a short hospital stay. Although it achieves good results in terms of survival in patients suffering from neuroendocrine metastases, it could also have a cytoreductive effect for other tumors. J. Surg. Oncol. 2000;74:24–29. © 2000 Wiley‐Liss, Inc.