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TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathology
Author(s) -
Pistello Mauro,
Morrica Antonietta,
Maggi Fabrizio,
Vatteroni Maria Linda,
Freer Giulia,
Fornai Claudia,
Casula Francesca,
Marchi Santino,
Ciccorossi Pietro,
Rovero Paolo,
Bendinelli Mauro
Publication year - 2001
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/1096-9071(20000201)63:2<189::aid-jmv1014>3.0.co;2-h
Subject(s) - virology , torque teno virus , virus , genotype , viral disease , population , hepatitis c virus , medicine , biology , immunology , genetics , environmental health , gene
TT virus (TTV) infection is extremely widespread in the general population. A sensitive real‐time PCR assay was developed that quantitated accurately the most prevalent TTV genotypes in Italy. When used to test 217 individuals for TTV viraemia, the overall prevalence was 94%. Viraemia levels varied widely amongst individual subjects, with no major differences related to gender or age. The highest TTV titres were in haemophiliacs and in patients with non‐A–E hepatitis, but they did not differ from the group with miscellaneous diseases. HIV‐ and HCV‐infected subjects and patients with primary liver diseases had TTV loads similar to those of healthy individuals. J. Med. Virol. 63:189–195, 2001. © 2001 Wiley‐Liss, Inc.