Premium
Rubella‐associated aplastic anemia treated by syngeneic stem cell transplantations
Author(s) -
Kook Hoon,
Kim Geun Mo,
Kim Hyeoung Joon,
Kim Chan Jong,
Yoon Won Sang,
Hwang Tai Ju
Publication year - 2000
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/1096-8652(200008)64:4<303::aid-ajh11>3.0.co;2-0
Subject(s) - aplastic anemia , medicine , immunology , stem cell , rubella , immune system , vaccination , biology , bone marrow , measles , genetics
A 14‐year‐old boy presented with aplastic anemia 3 months after contracting rubella. Stem cell transplantations from his identical twin were carried out. Successful engraftment occurred only when conditioning therapy was given prior to the infusion of the syngeneic stem cells, supporting an immune mechanism to explain the pathogenesis of virus‐associated aplastic anemia. Am. J. Hematol. 64:303–305, 2000. © 2000 Wiley‐Liss, Inc.