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Genetic structure of Quechua‐speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations
Author(s) -
Luiselli Donata,
Simoni Lucia,
TarazonaSantos Eduardo,
Pastor Santiago,
Pettener Davide
Publication year - 2000
Publication title -
american journal of physical anthropology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.146
H-Index - 119
eISSN - 1096-8644
pISSN - 0002-9483
DOI - 10.1002/1096-8644(200009)113:1<5::aid-ajpa2>3.0.co;2-u
Subject(s) - gene flow , genetic structure , cline (biology) , population , allele , biology , genetics , evolutionary biology , allele frequency , gene pool , geography , population genetics , genetic variation , gene , demography , genetic diversity , sociology
A sample of 141 Quechua‐speaking individuals of the population of Tayacaja, in the Peruvian Central Andes, was typed for the following 16 genetic systems: ABO, Rh, MNSs, P, Duffy, AcP1, EsD, GLOI, PGM1, AK, 6‐PGD, Hp, Gc, Pi, C3, and Bf. The genetic structure of the population was analyzed in relation to the allele frequencies available for other South Amerindian populations, using a combination of multivariate and multivariable techniques. Spatial autocorrelation analysis was performed independently for 13 alleles to identify patterns of gene flow in South America as a whole and in more specific geographic regions. We found a longitudinal cline for the AcP1*a and EsD*1 alleles which we interpreted as the result of an ancient longitudinal expansion of a putative ancestral population of modern Amerindians. Monmonnier's algorithm, used to identify areas of sharp genetic discontinuity, suggested a clear east‐west differentiation of native South American populations, which was confirmed by analysis of the distribution of genetic distances. We suggest that this pattern of genetic structures is the consequence of the independent peopling of western and eastern South America or to low levels of gene flow between these regions, related to different environmental and demographic histories. Am J Phys Anthropol 113:5–17, 2000. © 2000 Wiley‐Liss, Inc.