Open AccessMolecular Modeling of Nucleic Acid Structure: Energy and Sampling
Author(s) -
Bergonzo Christina,
GalindoMurillo Rodrigo,
Cheatham Thomas E.
Publication year - 2013
Publication title -
current protocols in nucleic acid chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1934-9289
pISSN - 1934-9270
DOI - 10.1002/0471142700.nc0708s54
Subject(s) - nucleic acid , nucleic acid structure , molecular mechanics , umbrella sampling , sampling (signal processing) , energy (signal processing) , computer science , chemistry , molecular dynamics , computational chemistry , biochemistry , physics , rna , quantum mechanics , filter (signal processing) , computer vision , gene
An overview of computer simulation techniques as applied to nucleic acid systems is presented. This unit discusses methods used to treat energy and to sample representative configurations. Emphasis is placed on molecular mechanics and empirical force fields. Curr. Protoc. Nucleic Acid Chem . 54:7.8.1‐7.8.21. © 2013 by John Wiley & Sons, Inc.