Premium
Synthesis and insecticidal activity of new amide derivatives of piperine
Author(s) -
Paula Vanderlúcia F de,
Barbosa Luiz C de A,
Demuner Antônio J,
PilóVeloso Dorila,
Picanço Marcelo C
Publication year - 2000
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/(sici)1526-4998(200002)56:2<168::aid-ps110>3.0.co;2-h
Subject(s) - piperine , piperaceae , piper , amide , yield (engineering) , exigua , biology , chemistry , toxicology , botany , biochemistry , spodoptera , pharmacology , materials science , gene , metallurgy , recombinant dna
The natural lipophilic amides piperine and piperiline were isolated from Piper nigrum L (Piperaceae). Piperine was hydrolysed into piperic acid (85% yield) which was converted into 16 amides (28–89% yield). The contact toxicity of all synthetic amides, and also that of piperine and piperiline, at the dose 10 µg per insect, was evaluated for the Brazilian economically important insects Ascia monuste orseis Latr, Acanthoscelides obtectus Say, Brevicoryne brassicae L, Protopolybia exigua DeSaus and Cornitermes cumulans Kollar. The results demontrated that the insects have different sensivities to the various amides, with mortality ranging from 0 to 97.5% according to the compound and insect species. © 2000 Society of Chemical Industry