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Successful lysis of right and left heart thrombus by tissue plasminogen activator
Author(s) -
Yeh KuanHung,
Hung KuoChun,
Lin FunChung,
Yeh SanJou,
Wu Delon
Publication year - 2000
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/(sici)1522-726x(200001)49:1<91::aid-ccd22>3.0.co;2-b
Subject(s) - medicine , cardiology , thrombus , intracardiac injection , tachycardia , tissue plasminogen activator , radiofrequency ablation , ablation , thrombosis , ventricular tachycardia , heart disease
Tissue plasminogen activator (t‐PA) was administered to three patients with newly developed intracardiac thrombi. Cases 1 and 2 developed right heart thrombi after radiofrequency ablation for atrioventricular nodal reentrant tachycardia and case 3 had tachycardia‐related cardiomyopathy and a left ventricular thrombus. In all three patients, the intracardiac thrombi were successfully eliminated following t‐PA therapy without major bleeding complications. These observations suggest that t‐PA is effective in lysing new thrombus complicating radiofrequency ablation or heart failure and may be the therapy of choice in these conditions. Cathet. Cardiovasc. Intervent. 49:91–96, 2000. © 2000 Wiley‐Liss, Inc.