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Applications of capillary electrophoresis with electrochemical detection in pharmaceutical and biomedical analyses
Author(s) -
Wang Anbao,
Fang Yuzhi
Publication year - 2000
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/(sici)1522-2683(20000401)21:7<1281::aid-elps1281>3.0.co;2-7
Subject(s) - capillary electrophoresis , amperometry , chromatography , electrophoresis , chemistry , capillary electrochromatography , capillary action , catechol , potentiometric titration , electrochemistry , electrode , materials science , biochemistry , composite material
As a high efficiency separation technique, capillary electrophoresis has been widely used in various fields of analytical science. This review discusses the applications of electrochemical detection systems combined with capillary electrophoresis in pharmaceutical and biomedical analysis. These detection methods mainly involve amperometric detection but also include conductivity detection and potentiometric detection. Its applications in the field are divided into six parts, including catechol compounds, thiols, amino acids and peptides, carbohydrates, general pharmaceuticals, and other related compounds. A relatively detailed discussion is described for each compound under the current studied. On this basis, we have suggested several conceivable directions for capillary electrophoresis with electrochemical detection in the future.