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The analysis of microbial proteomes: Strategies and data exploitation
Author(s) -
O'Connor C. David,
Adams Phillip,
Alefounder Peter,
Farris Michele,
Kinsella Niamh,
Li Yan,
Payot Sophie,
Skipp Paul
Publication year - 2000
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/(sici)1522-2683(20000401)21:6<1178::aid-elps1178>3.0.co;2-b
Subject(s) - exploit , proteome , computer science , data science , redundancy (engineering) , biochemical engineering , computational biology , field (mathematics) , biology , bioinformatics , engineering , mathematics , operating system , computer security , pure mathematics
Microbes present special opportunities for proteomic analysis that are not yet available for other types of organisms, due mainly to the relative abundance of information on their genomes, their low levels of functional redundancy and their experimental tractability. They are also being used to develop and validate powerful new experimental approaches that surmount some important current limitations in this field. The review surveys the different proteomic procedures that are available and considers the advantages and disadvantages of different experimental strategies. The ways in which microbiologists — and others — can exploit proteomic data are also discussed.