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Dielectrophoresis of human red cells in microchips
Author(s) -
Xu Chunxiang,
Wang Yan,
Cao Ming,
Lu Zuhong
Publication year - 1999
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/(sici)1522-2683(19990701)20:9<1829::aid-elps1829>3.0.co;2-b
Subject(s) - dielectrophoresis , electric field , electrode , dielectric , materials science , nanotechnology , microelectrode , optoelectronics , chemistry , physics , quantum mechanics
The dielectric properties of human red cells are strongly affected by the applied electric field, especially the frequency. Under the high frequency, the cells are acted on by positive dielectrophoresis (DEP) force and move to the tip region of the interdigitated electrode where the electric field is strongest. The cells are acted on by negative DEP force and aggregated in the “bay” zone between the neighboring electrode castellation tips and the surface of the electrodes. The patterns formed by DEP force are identical with the distribution of the electric field.