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A fully automated multicapillary electrophoresis device for DNA analysis
Author(s) -
Behr Sven,
Mätzig Martin,
Levin Alexander,
Eickhoff Holger,
Heller Christoph
Publication year - 1999
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/(sici)1522-2683(19990601)20:7<1492::aid-elps1492>3.0.co;2-v
Subject(s) - computer science , biomolecule , robustness (evolution) , electrophoresis , biological system , chromatography , chemistry , materials science , nanotechnology , biology , biochemistry , gene
We describe the construction and performance of a fully automated multicapillary electrophoresis system for the analysis of fluorescently labeled biomolecules. A special detection system allows the simultaneous spectral analysis of all 96 capillaries. The main features are true parallel detection without any moving parts, high robustness, and full compatibility to existing protocols. The device can process up to 40 microtiter plates (96 and 384 well) without human interference, which means up to 15 000 samples before it has to be reloaded.