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A Cytotoxic Acetophenone with a Novel Skeleton, Isolated from Cynanchum taiwanianum
Author(s) -
Huang PaoLin,
Won ShenJeu,
Day ShiowHwa,
Lin ChunNan
Publication year - 1999
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/(sici)1522-2675(19991006)82:10<1716::aid-hlca1716>3.0.co;2-o
Subject(s) - chemistry , acetophenone , cytotoxicity , rhizome , cytotoxic t cell , stereochemistry , in vitro , traditional medicine , organic chemistry , biochemistry , medicine , catalysis
A novel acetophenone, cynantetrone ( 1 ), was isolated from the rhizome of Cynanchum taiwanianum and its structure determined by spectroscopic methods. Compound 1 and cynandione B ( 3 ) showed significant in vitro cytotoxicity against T‐24 cell lines, and 3 also against PLC/PRF/5 cell lines.