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Synthesis of Stable Cyclic Sulfinamides with a Hydroperoxy Function by Oxidation of Isothiazolium Salts
Author(s) -
Hartung Christine,
Illgen Katrin,
Sieler Joachim,
Schneider Bernd,
Schulze Bärbel
Publication year - 1999
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/(sici)1522-2675(19990505)82:5<685::aid-hlca685>3.0.co;2-4
Subject(s) - chemistry , aryl , function (biology) , medicinal chemistry , stereochemistry , organic chemistry , alkyl , evolutionary biology , biology
The oxidation of isothiazolium salts 4 to stable 2‐aryl‐2,3,4,5,6,7‐hexahydro‐3‐hydroperoxy‐1,2‐benzisothiazole 1‐oxides rac‐cis ‐ 6 (sultims) as a new class of cyclic sulfinamides is described. The formations of the oxidation products rac‐cis ‐ 6 as well as 3‐hydroperoxy and 3‐hydroxy sultams, 8 and 9 , respectively, and isothiazol‐3(2 H )‐one 1,1‐dioxides 10 are presented.