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Correction for B 1 and B 0 variations in quantitative T 2 measurements using MRI
Author(s) -
Sled John G.,
Pike G. Bruce
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(200004)43:4<589::aid-mrm14>3.0.co;2-2
Subject(s) - imaging phantom , field strength , nuclear magnetic resonance , voxel , magnetic resonance imaging , computer science , field (mathematics) , signal (programming language) , physics , magnetic field , computational physics , artificial intelligence , mathematics , optics , medicine , radiology , quantum mechanics , pure mathematics , programming language
A new method is described for compensating for the bias introduced by variations in radiofrequency (RF) field strength and main magnetic field strength when making quantitative T 2 measurements using MRI. Field measurements made during the MRI study are used in combination with a signal model for off‐resonance and imperfect RF pulses to correct the estimated T 2 value at every voxel. Applicable to both multicomponent and conventional single‐component T 2 studies, the method has been validated experimentally using paramagnetic salt solutions in a multicompartment phantom. Studies of the human head are used to demonstrate the method in practice. Magn Reson Med 43:589–593, 2000. © 2000 Wiley‐Liss, Inc.