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In vivo intermolecular double‐quantum imaging on a clinical 1.5 T MR scanner
Author(s) -
Zhong Jianhui,
Chen Zhong,
Kwok Edmund
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(200003)43:3<335::aid-mrm3>3.0.co;2-1
Subject(s) - coherence (philosophical gambling strategy) , intermolecular force , scanner , quantum , nuclear magnetic resonance , sensitivity (control systems) , physics , chemistry , quantum mechanics , optics , molecule , electronic engineering , engineering
A novel MRI method based on the intermolecular double‐quantum coherence (DQC) for soft tissues is described. DQC images of human brain were obtained for the first time on a whole‐body 1.5 T scanner. The combination of quantum and classical formalisms was used to characterize multiple‐quantum coherences, and to aid in the design of a DQC imaging sequence. The theoretical analysis suggests that signals from the intermolecular DQCs have higher sensitivity than those from the zero‐quantum coherence (ZQC) for human brain, and the sensitivity increases with increased field strength. The DQC signal may provide a new form of contrast for MRI. Magn Reson Med 43:335–341, 2000. © 2000 Wiley‐Liss, Inc.