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Validation of MR‐based polymer gel dosimetry as a preclinical three‐dimensional verification tool in conformal radiotherapy
Author(s) -
De Deene Y.,
De Wagter C.,
Van Duyse B.,
Derycke S.,
Mersseman B.,
De Gersem W.,
Voet T.,
Achten E.,
De Neve W.
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(200001)43:1<116::aid-mrm14>3.0.co;2-5
Subject(s) - dosimetry , imaging phantom , materials science , nuclear medicine , biomedical engineering , medicine
The aim of this work was to investigate MR‐based polymer gel dosimetry as a three‐dimensional (3D) dosimetry technique in conformal radiotherapy. A cylindrical container filled with polymer gel was placed in a water‐filled torso phantom to verify a treatment plan for the conformal irradiation of a mediastinal tumor located near the esophagus. Magnetic resonance spin‐spin relaxation rate images were acquired and, after calibration, converted to absorbed dose distributions. The dose maps were compared with dose distributions measured using radiographic film. The average root‐mean‐square structural deviation, for the complete dose distribution, amounted to less than 3% between gel and film dose maps. It may be expected that MR gel dosimetry will become a valuable tool in the verification of 3D dose distributions. The influence of imaging artifacts arising from eddy currents, temperature drift during scanning, and B1 field inhomogeneity on the dose maps was taken into account and minimized. Magn Reson Med 43:116–125, 2000. © 2000 Wiley‐Liss, Inc.