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Analysis of periprosthetic capsular tissue from women with silicone breast implants by magic‐angle spinning NMR
Author(s) -
Garrido Leoncio,
Young V. Leroy
Publication year - 1999
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(199909)42:3<436::aid-mrm5>3.0.co;2-i
Subject(s) - silicone , capsular contracture , polydimethylsiloxane , materials science , breast augmentation , periprosthetic , magic angle , magic angle spinning , biomedical engineering , implant , chemistry , nuclear magnetic resonance spectroscopy , composite material , medicine , surgery , arthroplasty , organic chemistry , cancer , breast cancer , breast reconstruction
The amount of silicone (polydimethylsiloxane [PDMS]) in capsular tissue surgically removed from women with breast implants was measured by using 29 Si and 1 H magic‐angle spinning solid‐state NMR spectroscopy. Twelve women having smooth surface silicone gel‐filled implants, including a subject with “low‐bleed” double‐lumen implants, had detectable levels of PDMS ranging from 0.05 to 9.8% silicon in wet tissue (w/w). No silicon‐containing compounds other than PDMS were detected. No correlation was found between the amount of PDMS measured in the capsular tissue and the length of implantation time (Pearson correlation coefficient, r = 0.22). The results showed no relationship between higher amounts of PDMS and capsular contracture ( p = 0.74) or other symptoms ( p = 0.53). Magn Reson Med 42:436–441, 1999. © 1999 Wiley‐Liss, Inc.