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Dynamic imaging of perfusion in human skeletal muscle during exercise with arterial spin labeling
Author(s) -
Frank Lawrence R.,
Wong Eric C.,
Haseler Luke J.,
Buxton Richard B.
Publication year - 1999
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(199908)42:2<258::aid-mrm7>3.0.co;2-e
Subject(s) - perfusion , skeletal muscle , arterial spin labeling , calf muscle , perfusion scanning , medicine , arterial perfusion , cardiology , nuclear medicine , anatomy
MR images acquired by using an arterial spin‐labeling technique showed spatial and temporal variations of perfusion in the skeletal muscle of exercising humans. Perfusion measurements made during plantar flexion exercise in normal volunteers were consistent with those obtained by traditional techniques reported in the literature. Spatial heterogeneity of perfusion values clearly delineated the various muscle groups within the lower leg. These results are interpreted in terms of a quantitative model for the perfusion signal in muscle. This method can provide a useful tool in the study of muscle physiology. Magn Reson Med 42:258–267, 1999. Published 1999 Wiley‐Liss, Inc.