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Magnetic resonance imaging of frozen tissues: Temperature‐dependent MR signal characteristics and relevance for MR monitoring of cryosurgery
Author(s) -
Daniel Bruce L.,
Butts Kim,
Block Walter F.
Publication year - 1999
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(199903)41:3<627::aid-mrm28>3.0.co;2-q
Subject(s) - magnetic resonance imaging , cryosurgery , nuclear magnetic resonance , signal (programming language) , materials science , medicine , radiology , physics , computer science , programming language
Previously, the magnetic resonance (MR) imaging appearance of frozen tissues created during cryosurgery has been described as a signal void. In this work, very short echo times (1.2 msec) allowed MR signals from frozen tissues to be measured at temperatures down to −35°C. Ex vivo bovine liver, muscle, adipose tissue, and water were imaged at steady‐state temperatures from −78° to +6°C. Signal intensity, T2*, and T1 were measured using gradient‐echo imaging. Signal intensity and T2* decrease monotonically with temperature. In the future, these MR parameters may be useful for mapping temperatures during cryosurgery. Magn Reson Med 41:627–630, 1999. © 1999 Wiley‐Liss, Inc.