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Noninvasive determination of coronary blood flow velocity with magnetic resonance imaging: Comparison of breath‐hold and navigator techniques with intravascular ultrasound
Author(s) -
Nagel Eike,
Bornstedt Axel,
Hug Jürgen,
Schnackenburg Bernhard,
Wellnhofer Ernst,
Fleck Eckart
Publication year - 1999
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(199903)41:3<544::aid-mrm17>3.0.co;2-s
Subject(s) - magnetic resonance imaging , blood flow , coronary artery disease , medicine , temporal resolution , intravascular ultrasound , nuclear medicine , ultrasound , limits of agreement , radiology , cardiology , physics , quantum mechanics
The aim of this study was to evaluate two different magnetic resonance (MR) techniques for the noninvasive assessment of intracoronary blood flow. Coronary blood flow velocities were measured invasively in 26 angiographically normal segments of 12 patients. Noninvasive measurements were performed in identical segments with two MR techniques using a 1.5 T MR tomograph (ACS NT, Philips). A single breath‐hold technique (temporal resolution: 140 msec) and a similar non‐breath‐hold technique with prospective navigator correction and improved temporal resolution (45 msec) were used. Maximal coronary flow velocities determined by MR correlated closely with invasive measurements (breath‐hold: r = 0.70; navigator: r = 0.86); however, a significant underestimation of the MR measurements was found (slope = 0.33 and 0.37). The relative difference from the invasive method was lower for the navigator technique compared with the breath‐hold technique ( P < 0.02). Both MR techniques allow the determination of coronary blood flow velocities. The higher temporal resolution and shorter acquisition window of navigator‐corrected non‐breath‐hold techniques lead to increased accuracy. This approach is a further step toward the diagnostic use of MR flow measurements in coronary artery disease. Magn Reson Med 41:544–549, 1999. © 1999 Wiley‐Liss, Inc.