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Quantification of dynamic changes in cerebral venous oxygenation with MR phase imaging at 1.9 T
Author(s) -
Liu Yijun,
Pu Yonglin,
Fox Peter T.,
Gao JiaHong
Publication year - 1999
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/(sici)1522-2594(199902)41:2<407::aid-mrm27>3.0.co;2-4
Subject(s) - oxygenation , blood oxygenation , venous blood , magnetic resonance imaging , cerebral veins , medicine , functional magnetic resonance imaging , nuclear magnetic resonance , nuclear medicine , radiology , physics
A double‐echo magnetic resonance (MR) phase imaging method was used to measure the time‐dependent changes in regional cerebral venous blood oxygenation during neural stimulation. Our results showed that a finger opposition task induced an absolute increase of blood oxygenation level of Δ Y = 0.16 ± 0.05 ( n = 6), which was measured in the small veins located in the left central sulcus. It was observed that there is a long temporal delay of approximately 27 sec after the onset of the task to reach the steady‐state venous oxygenation. This work demonstrated that MRI is a powerful clinical tool for in vivo monitoring of the dynamic nature of organ‐specific venous blood oxygenation.Magn Reson Med 41:407–411, 1999. © 1999 Wiley‐Liss, Inc.