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Characterization of breast lesion morphology with delayed 3DSSMT: An adjunct to dynamic breast MRI
Author(s) -
Leong Cindy S.,
Daniel Bruce L.,
Herfkens Robert J.,
Birdwell Robyn L.,
Jeffrey Stefanie S.,
Ikeda Debra M.,
SawyerGlover Anne M.,
Glover Gary H.
Publication year - 2000
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(200002)11:2<87::aid-jmri3>3.0.co;2-e
Subject(s) - malignancy , magnetic resonance imaging , medicine , breast mri , dynamic contrast enhanced mri , radiology , bi rads , breast imaging , breast tumor , flip angle , pathology , mammography , breast cancer , cancer
The purpose of the study was to determine the sensitivity and specificity of various morphologic criteria in distinguishing malignant from benign breast lesions using a new sequence (3DSSMT) performed immediately after dynamic breast MRI. 3DSSMT combines a water‐selective spectral‐spatial excitation and an on‐resonance magnetization transfer pulse with three‐dimensional spoiled gradient‐echo imaging. Morphologic features of 87 pathologically confirmed lesions were analyzed. The presence of either skin thickening, or a combination of a spiculated or microlobulated border, with a rim, ductal, linear, or clumped enhancement pattern was 94% specific and 54% sensitive for malignancy. Conversely, the presence of either a perfectly smooth border, a well‐defined margin, non‐enhancing internal septations, or a macrolobulated border was 97% specific and 35% sensitive for a benign diagnosis. In conclusion, delayed 3DSSMT discriminates a significant number of benign and malignant breast lesions; it has the potential to improve the diagnostic accuracy of dynamic breast MRI. J. Magn. Reson. Imaging 2000;11:87–96. © 2000 Wiley‐Liss, Inc.