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Magnetization transfer imaging of the brain: A quantitative comparison of results obtained at 1.5 and 4.0 t
Author(s) -
Duvvuri Umamaheswar,
Roberts David A.,
Leigh J. S.,
Bolinger Lizann
Publication year - 1999
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(199910)10:4<527::aid-jmri5>3.0.co;2-0
Subject(s) - magnetization transfer , contrast (vision) , nuclear magnetic resonance , materials science , magnetization , signal to noise ratio (imaging) , image quality , perfusion scanning , magnetic resonance imaging , nuclear medicine , biomedical engineering , optics , physics , magnetic field , perfusion , medicine , radiology , computer science , artificial intelligence , quantum mechanics , image (mathematics)
The preliminary results of magnetization transfer (MT) imaging on a whole body 4.0 T system are presented. Cooked egg phantoms and several volunteers were imaged on 1.5 and 4.0 T magnets interfaced to GE Signa scanners. The MT ratio (MTR), signal difference to noise ratio (SDNR), and contrast parameters were measured at both fields and compared. Furthermore, single‐shot Z‐spectroscopy was used to characterize the frequency dependence of the MT phenomenon. The results show that MT imaging can be safely performed at 4.0 T without exceeding limitations of radio frequency power. The MT effect is more pronounced at the higher field, leading to better quality images with higher contrast and SDNR. The Z‐spectra are not markedly different at the higher field although the MTR is greater. The potential applications of this technique to study neurodegenerative diseases, as well as, perfusion imaging and angiography are discussed. J. Magn. Reson. Imaging 1999;10:527–532. © 1999 Wiley‐Liss, Inc.