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Demonstration of gravity‐dependent lung perfusion with contrast‐enhanced magnetic resonance imaging
Author(s) -
Stock Klaus W.,
Chen Qun,
Levin David,
Hatabu Hiroto,
Edelman Robert R.
Publication year - 1999
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(199904)9:4<557::aid-jmri8>3.0.co;2-y
Subject(s) - supine position , magnetic resonance imaging , perfusion , contrast (vision) , lung , nuclear medicine , medicine , intensity (physics) , dynamic contrast , nuclear magnetic resonance , prone position , physics , radiology , optics
Imaging of lung perfusion using contrast‐enhanced dynamic magnetic resonance (MR) was performed in both the supine and prone positions in six volunteers. Regions of interest (ROIs) were chosen in the dependent and non‐dependent portions of the right lung. The percentage increase in signal intensity (SI) and the mean slope were calculated. In the supine position, the dorsal ROI had a greater increase in SI (236.0% vs. 156.9%, P < 0.05) and a faster rise in the slope of enhancement (55.1%/sec vs. 30.1%/sec, P < 0.05) than the ventral ROI. After changing to the prone position, higher peak enhancement (234.3% vs. 177.4%, P < 0.05) and faster slopes (59.6%/sec vs. 35.3%/sec, P < 0.05) shifted to the anterior ROI. We conclude that dynamic contrast‐enhanced MR imaging is sensitive to demonstrate gravitationally dependent differences in lung perfusion. J. Magn. Reson. Imaging 1999;9:557–561. © 1999 Wiley‐Liss, Inc.