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Differentiation between the effects of T 1 and T 2 * shortening in contrast‐enhanced MRI of the breast
Author(s) -
Kuperman Vadim Yu.,
Alley Marcus T.
Publication year - 1999
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(199902)9:2<172::aid-jmri4>3.0.co;2-g
Subject(s) - magnetic resonance imaging , gadolinium , breast mri , contrast (vision) , medicine , in vivo , radiology , dynamic contrast enhanced mri , lesion , nuclear magnetic resonance , nuclear medicine , pathology , chemistry , breast cancer , mammography , computer science , biology , cancer , physics , microbiology and biotechnology , organic chemistry , artificial intelligence
The purpose of this study is to describe a technique for magnetic resonance imaging (MRI) that can potentially improve identification of malignant tissue in the human breast. The suggested MRI technique is based on the differentiation between two competing effects leading to opposite changes in image intensity, namely, T 1 and T 2 * shortening caused by administration of gadolinium chelate. The proposed approach also allows calculation of changes in the R 2 * relaxation rate in breast tissue. The feasibility of the technique for in vivo MRI and increased lesion contrast is demonstrated. The results indicate that this technique may improve detection of malignant breast tissue. J. Magn. Reson. Imaging 1999;9:172–176. © 1999 Wiley‐Liss, Inc.