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MRI of primary lymphoma of bone: Cortical disorder as a criterion for differential diagnosis
Author(s) -
Häussler Marc D.,
Fenstermacher Marc J.,
Johnston Dennis A.,
Harle Thomas S.
Publication year - 1999
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(199901)9:1<93::aid-jmri13>3.0.co;2-d
Subject(s) - osteosarcoma , medicine , sarcoma , magnetic resonance imaging , differential diagnosis , lymphoma , pathology , primary bone , radiology , soft tissue
To investigate the pattern and dimension of cortical bone abnormality on magnetic resonance imaging (MRI) as a feature to distinguish primary lymphoma of bone from osteosarcoma and Ewing sarcoma, 46 patients with primary malignant bone lesions with a soft tissue mass (16 osteosarcomas, 15 Ewing sarcomas, 15 lymphomas) were examined with MRI (T1‐weighted pre‐/postcontrast spin‐echo sequences and T2‐weighted spin‐echo and fast spin‐echo sequences; 1.5 T system). Qualitative image analysis revealed no differences for signal characteristics and enhancement. Lymphomas appeared significantly more often homogeneous (47%; Ewing sarcoma 20%; osteosarcoma 6%), and patients were significantly older (cutoff point 30 years). Lymphomas showed significantly less frequent cortical abnormality (60%; Ewing sarcoma 87%; osteosarcoma 100%), complete penetration (13%; Ewing sarcoma 67%; osteosarcoma 87%), focal destruction (13%; Ewing sarcoma 40%; osteosarcoma 81%), and complete destruction (0%; Ewing sarcoma 13%; osteosarcoma 19%). In conclusion, primary lymphoma of bone is characterized by minimal cortical changes despite an accompanying soft tissue mass in a patient over 30 years of age. J. Magn. Reson. Imaging 1999;9:93–100 © 1999 Wiley‐Liss, Inc.