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Extraslice spin tagging (EST) magnetic resonance imaging for the determination of perfusion
Author(s) -
Berr Stuart S.,
Mai Vu Minh
Publication year - 1999
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/(sici)1522-2586(199901)9:1<146::aid-jmri19>3.0.co;2-c
Subject(s) - spins , physics , magnetic resonance imaging , nuclear magnetic resonance , pulse sequence , image plane , magnetization , magnetization transfer , spin echo , perfusion scanning , radiofrequency coil , electromagnetic coil , optics , perfusion , magnetic field , condensed matter physics , medicine , computer science , radiology , image (mathematics) , artificial intelligence , quantum mechanics
A new magnetic resonance technique to measure perfusion is described in detail. The means by which this is done is to invert all the spins in the radiofrequency RF coil with a non‐spatially selective pulse and immediately re‐invert the spins in the imaging plane. The net effect is that the spins in the imaging plane experience minimal perturbation of their magnetization while the spins outside the plane (extraslice) are inverted, or tagged. Tagged spins that flow into the imaging plane before image data are acquired decrease the signal intensity in the imaging plane when compared with an image in which the inflowing spins are not tagged. This decrease in signal can be used to calculate the number of spins that have flowed into the imaging plane, i.e., can be used to calculate the perfusion in mL · 100 g tissue −1 · min −1 . The extraslice spin tagging (EST) magnetization preparation period was coupled with a fast imaging sequence to obtain perfusion maps for normal volunteers. J. Magn. Reson. Imaging 1999;9:146–150 © 1999 Wiley‐Liss, Inc.