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Synthesis and Potential Muscarinic Receptor Binding and Antioxidant Properties of 3‐(Thiadiazolyl)pyridine 1‐Oxide Compounds
Author(s) -
Martinez Ana,
Alonso Diana,
Castro Ana,
Arán Vicente J.,
Cardelús Ignasi,
Baños Josep E.,
Badia Albert
Publication year - 1999
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/(sici)1521-4184(19996)332:6<191::aid-ardp191>3.0.co;2-x
Subject(s) - chemistry , pyridine , muscarinic acetylcholine receptor , moiety , antioxidant , stereochemistry , receptor , medicinal chemistry , organic chemistry , biochemistry
The synthesis of two different series of 3‐(thiadiazolyl)pyridine 1‐oxides containing 1,2,5‐ and 1,2,4‐thiadiazole moiety respectively is described. The potential muscarinic receptor binding together with the antioxidant properties of the new compounds were evaluated.