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Potentiometric Titration of 2‐Thiouracils
Author(s) -
Ciesielski Witold,
Zakrzewski Robert
Publication year - 1998
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/(sici)1521-4184(199811)331:11<371::aid-ardp371>3.0.co;2-z
Subject(s) - potentiometric titration , chemistry , thiouracil , iodine , titration , inorganic chemistry , nuclear chemistry , chromatography , organic chemistry , ion , thyroid , medicine
A new method is presented for the determination of 100–500 μmol of 6‐methyl‐2‐thiouracil and 6‐benzyl‐2‐thiouracil which utilises their reaction with iodine in an alkaline medium with potentiometric end‐point detection. Elaborated methods were applied to the determination of 2‐thiouracils in drugs.