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Effect of pH on Sodium Usnate Thermostability in Dilute Aqueous Solutions
Author(s) -
Coiffard C.,
Coiffard L. J. M.,
Peigne G.,
De RoeckHoltzhauer Y.
Publication year - 1998
Publication title -
archiv der pharmazie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 61
eISSN - 1521-4184
pISSN - 0365-6233
DOI - 10.1002/(sici)1521-4184(199804)331:4<128::aid-ardp128>3.0.co;2-1
Subject(s) - thermostability , chemistry , aqueous solution , sodium , isothermal process , kinetics , degradation (telecommunications) , nuclear chemistry , chromatography , inorganic chemistry , organic chemistry , thermodynamics , enzyme , telecommunications , physics , quantum mechanics , computer science
The objective of this study is the evaluation of sodium usnate thermostability. To this end, we used an isothermal method at four temperatures (40, 50, 60, and 70°C). The thermodegradation of dilute aqueous solutions of sodium usnate was studied at various pH values. This degradation appeared to follow first‐order kinetics. Under the best stability conditions (pH = 8), the experiments gave a t 90% of 54.58 days, and a t 90% of 359.07 days at 20°C.