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A New Concept for Operating Simulated Moving‐Bed Processes
Author(s) -
Kloppenburg E.,
Gilles E. D.
Publication year - 1999
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/(sici)1521-4125(199910)22:10<813::aid-ceat813>3.0.co;2-g
Subject(s) - throughput , volume (thermodynamics) , simulated moving bed , constant (computer programming) , process engineering , solvent , process (computing) , interval (graph theory) , surface area to volume ratio , chemistry , materials science , chromatography , mechanics , computer science , chemical engineering , thermodynamics , engineering , mathematics , physics , organic chemistry , adsorption , telecommunications , combinatorics , wireless , programming language , operating system
The simulated moving‐bed process (SMB) is used for continuous chromatographic separation in chemical engineering and biotechnology. In the usual operating scheme of SMB processes, the operating parameters, namely, the fluid volume flows, are kept constant. In this contribution, a new way of operating the process with volume flows varied within each switching interval is suggested. It is shown that the solvent consumption can be reduced substantially for a given feed throughput. Alternatively, the purity can be increased while keeping both the solvent consumption and the throughput constant.