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Separation of Enantiomers by Liquid‐Liquid Counter Current Chromatography
Author(s) -
Buchholz Kay,
Schulte Birgit,
Gmehling Jürgen,
Martens Jürgen
Publication year - 1998
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/(sici)1521-4125(199805)21:5<404::aid-ceat404>3.0.co;2-0
Subject(s) - enantiomer , chromatography , resolution (logic) , countercurrent chromatography , chemistry , high performance liquid chromatography , supercritical fluid chromatography , chromatographic separation , organic chemistry , computer science , artificial intelligence
Chromatographic resolution of enantiomers has been carried out with standard techniques (i.e., HPLC, GC, and TLC) using a chiral selector that is linked to the solid phase. Using liquid‐liquid counter current chromatography (LLCCC), the type and amount of chiral selector can be changed more easily. The authors present and discuss the use and advantages of LLCCC for the separation of enantiomers.