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Application of Adsorptive Stripping Voltammetry to the Determination of Trace Levels of Titanium in Mice Organs
Author(s) -
Pereira Maria do Carmo,
Pereira Maria de Lourdes
Publication year - 1999
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199911)11:16<1207::aid-elan1207>3.0.co;2-y
Subject(s) - adsorptive stripping voltammetry , chemistry , titanium , voltammetry , atomic absorption spectroscopy , mandelic acid , stripping (fiber) , trace metal , microelectrode , chromatography , metal , inorganic chemistry , analytical chemistry (journal) , electrode , electrochemistry , materials science , physics , organic chemistry , quantum mechanics , composite material
Trace levels of titanium (Ti) in mice organs were determined by adsorptive stripping voltammetry (AdSV) using mercury film microelectrodes (MFM). The method is based on the interfacial accumulation of Ti(IV)/mandelic acid complex by absorption at the potential of –0.15 V onto the MFM in the presence of mandelic acid 5.00×10 –3 mol/L and potassium chlorate 4.00×10 –2 mol/L at pH 3.4–3.5. The dependence of the peak current on different experimental variables is reported. The results achieved by AdSV were compared to those obtained by atomic absorption spectrometry (AAS) to guarantee the accuracy of the electroanalytical method developed. A significant accumulation of titanium was seen in the mice spleen, liver and the kidney under the test conditions described here. The histological studies showed that this metal was relatively well tolerated and did not induce abnormal morphological changes in the cells of the organs studied during the time of study.