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New Composite Modified Carbon Microfibers for Sensitive and Selective Determination of Physiologically Relevant Concentrations of Nitric Oxide in Solution
Author(s) -
Pontié Maxime,
Bedioui Fethi,
Devynck Jacques
Publication year - 1999
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199908)11:12<845::aid-elan845>3.0.co;2-d
Subject(s) - nafion , nip , resorcinol , chemistry , inorganic chemistry , nuclear chemistry , materials science , electrode , organic chemistry , electrochemistry , composite material
In this study, we have prepared nitric oxide (NO) microsensors using four combinations of nickel porphyrin (NiP), o ‐phenylenediamine ( o ‐PD), m ‐phenylenediamine ( m ‐PD), resorcinol and Nafion based layers to modify the surface of 8 μm diameter carbon fiber electrodes. We have compared the performances of the obtained composite microsensors (NiP/Nafion, Nafion/ o ‐PD, Nafion/( m ‐PD+resorcinol), and NiP/Nafion/ o ‐PD, respectively) in our home operating conditions. Our results indicate that Nafion/ o ‐PD and Nafion/( m ‐PD+resorcinol) microsensors are capable of detecting NO very selectively against nitrites, ascorbate, L ‐arginine, serotonine and xanthine. But these microsensors have a poorer sensitivity to NO than the NiP/Nafion/ o ‐PD microsensor. If selectivity is not a concern, NiP/Nafion, Nafion/ o ‐PD and NiP/Nafion/ o ‐PD microsensors are the most sensitive to NO concentrations as low as 40 nmol L –1 .