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Factors Affecting the Potentiometric Evaluation of K + in Protein Containing Solutions
Author(s) -
Oliveira Cristina M. R. R.,
Rebelo M. J. F.,
Camões M. F. G. F. C.
Publication year - 1999
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199907)11:10/11<825::aid-elan825>3.0.co;2-#
Subject(s) - potentiometric titration , chemistry , environmental chemistry , chromatography , analytical chemistry (journal) , inorganic chemistry , electrode
The attractive features of potentiometric analysis have contributed to its widespread application and motivated research in related topics. Clinical analysis is one of the domains where the analysis of ionized species takes particular relevance. Matrix effects on K + ISE membranes of different composition as well as on the liquid junction affect the results of potentiometric measurements. As a consequence specific action is required, particularly in terms of membrane composition, reference half‐cell, preparation of protein containing solutions and measurement procedures. This work aims at minimizing and discriminating the protein effects on blood electrolyte measurements with ISE. It is based on a series of studies concerning valinomycin based electrodes in PVC and in PU membrane matrices, hypertonic (saturated calomel) and isotonic calomel and silver‐silver chloride reference electrodes and batch and flow potentiometric measurements of K + in protein containing solutions.