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A Novel Electrochemical Microsensor for Nitric Oxide Based on Electropolymerized Film of o ‐Aminobenzaldehyde‐ethylene‐diamine Nickel
Author(s) -
Tu Huiping,
Mao Lanqun,
Cao Xuni,
Jin Litong
Publication year - 1999
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199901)11:1<70::aid-elan70>3.0.co;2-1
Subject(s) - detection limit , amperometry , electrochemistry , nickel , nitrite , chemistry , ethylene oxide , diamine , ethylene diamine , electrochemical gas sensor , nitric oxide , selectivity , materials science , inorganic chemistry , nuclear chemistry , polymer , electrode , polymer chemistry , chromatography , organic chemistry , catalysis , copolymer , nitrate
A novel electrochemical microsensor for nitric oxide (NO) is described. The microsensor, which is based on an electropolymerized film of o ‐aminobenzaldehyde‐ethylene‐diamine nickel [Ni(ABED)] and Nafion, shows a low detection limit, high selectivity and sensitivity to NO determination. The oxidation current (measured by differential pulse amperometric method) is linear with NO concentration ranging from 1.0×10 −8 to 1.0×10 −6 mol/L with a calculated detection limit, at a signal‐to‐noise ratio of three, equal to 5.0×10 −9 mol/L and a linear coefficient of 0.9921. Some endogenous electroactive substances in biological tissues, such as ascorbate, dopamine, 5‐hydroxytryptamine, cysteine and nitrite do not interfere with NO determination at the concentrations higher than those in biological systems. The microsensor should be promising for in vivo measurement of NO. The mechanism of the response of the microsensor to NO is preliminary studied.