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9,10‐Anthraquinone Modified Glassy Carbon Electrode and Its Application for Hemoglobin Determination
Author(s) -
Zhu Zhiwei,
Li NanQiang
Publication year - 1998
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199807)10:9<643::aid-elan643>3.0.co;2-6
Subject(s) - anthraquinone , hemoglobin , electrochemistry , redox , electrode , chemistry , glassy carbon , differential pulse voltammetry , phosphate buffered saline , peak current , analytical chemistry (journal) , inorganic chemistry , cyclic voltammetry , nuclear chemistry , chromatography , organic chemistry
The electrochemical behavior of a glassy carbon electrode modified with 9,10‐anthraquinone has been investigated in the absence and presence of hemoglobin. The stability of the modified electrode is satisfactory. Cyclic voltammogram of 9,10‐anthraquinone modified electrode in 0.15 mol L −1 pH 7.0 phosphate buffer exhibits a redox wave at −0.557 V (vs. SCE). Upon adding hemoglobin in solution, both of the reduction and oxidation currents decrease with increasing peak separation. It was found that the decrease of differential pulse voltammetric current was proportional to the concentration of hemoglobin over the range from 5.0 × 10 −8 to 3.0 × 10 −7 mol L −1 and from 3.0 × 10 −7 to 1.0 × 10 −6 mol L −1 (with correlation coefficients of 0.9971 and 0.9982, respectively). A satisfactory result was obtained for the determination of hemoglobin in clinical blood samples.