Premium
The Cathodic Stripping Voltammetric Determination of 6‐Mercaptopurine at a Silver Electrode
Author(s) -
Zeng Baizhao,
Purdy William C.
Publication year - 1998
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199804)10:4<236::aid-elan236>3.0.co;2-s
Subject(s) - stripping (fiber) , cathodic stripping voltammetry , cathodic protection , chemistry , electrode , analytical chemistry (journal) , bromide , reference electrode , inorganic chemistry , materials science , chromatography , electrochemistry , composite material
Voltammetric studies have been carried out on 6‐mercaptopurine (6MP) deposited at a silver electrode. 6MP yields a cathodic stripping signal at about –1.0 V (vs. Ag/AgCl) in pH 7.2 sodium phosphate buffer. Under selected conditions a linear calibration plot was obtained over the range of 0.2–6 μM with a relative standard derivation of 2.9 % for 1 μM 6MP ( n = 11, t d = 60 s). The voltammetric response of 6MP was dependent on experimental conditions such as solution pH and potential‐scan range. Generally 6MP exhibits two adjacent peaks in acidic solutions (pH < 6, C < 0.1 mM), a sharp peak in pH 6–9 solutions, and a broad wave with a small peak in basic solutions (pH > 9). Cetyltrimethylammonium bromide causes an enhancement of the cathodic stripping peak.