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A Self‐Contained Glucose Sensor Chip with Arrayed Capillaries
Author(s) -
Hiratsuka Atsunori,
Sasaki Satoshi,
Karube Isao
Publication year - 1998
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/(sici)1521-4109(199804)10:4<231::aid-elan231>3.0.co;2-b
Subject(s) - glucose oxidase , capillary action , hydrogen peroxide , wafer , electrode , platinum , materials science , biosensor , electrochemistry , silicon , analytical chemistry (journal) , optoelectronics , chemistry , nanotechnology , chromatography , composite material , catalysis , biochemistry , organic chemistry
A circular arrayed sensor which integrates a number of linear capillaries and enzyme immobilized platinum electrodes on a silicon wafer has been developed. This sensor device has no need of other electrical or mechanical devices, because the sample solution is introduced by capillary action. The sensor was fabricated using silicon semiconductor technology, allowing mass production of a miniature sensor. Each linear unit is a self‐contained device. Glucose solution is drawn into a capillary by surface tension, reacts with immobilized glucose oxidase and produces hydrogen peroxide (H 2 O 2 ). The electrochemical signal due to the oxidation of H 2 O 2 is measured using a sputtered platinum electrode. This sensor device is capable of measuring glucose concentration ranging from 10 to 200 mM.