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Single‐Molecule Force Spectroscopy on Xanthan by AFM
Author(s) -
Li Hongbin,
Rief Matthias,
Oesterhelt Filipp,
Gaub Hermann E.
Publication year - 1998
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/(sici)1521-4095(199803)10:4<316::aid-adma316>3.0.co;2-a
Subject(s) - force spectroscopy , materials science , atomic force microscopy , molecule , spectroscopy , nanotechnology , organic chemistry , chemistry , physics , quantum mechanics
Single‐molecule force spectroscopy , a new technique that is useful for exploring the mechanical properties of single polymer coils and also for examining polymers with specific secondary structures, is described. The Figure shows the principle of the experiment. A thin layer of the sample is placed on a piezo crystal and stretched using the tip of the atomic force microscope, allowing force–extension curves to be derived.