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Synthesis of new side‐chain polyrotaxanes via free radical polymerization of a water‐soluble semi‐rotaxane monomer consisting of 2,6‐dimethyl‐β‐cyclodextrin and 3‐ O ‐(11‐acryloylaminoundecanoyl)cholic acid
Author(s) -
Noll Olaf,
Ritter Helmut
Publication year - 1998
Publication title -
macromolecular chemistry and physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.57
H-Index - 112
eISSN - 1521-3935
pISSN - 1022-1352
DOI - 10.1002/(sici)1521-3935(19980501)199:5<791::aid-macp791>3.0.co;2-o
Subject(s) - monomer , chemistry , polymer chemistry , rotaxane , polymerization , side chain , cyclodextrin , radical polymerization , polymer , solvent , radical initiator , supramolecular chemistry , organic chemistry , molecule
The synthesis of a new water‐soluble semi‐rotaxane monomer consisting of threaded 2,6‐dimethyl‐β‐cyclodextrin on a 3‐ O ‐(11‐acryloylaminoundecanoyl)cholic acid guest component is described. This new monomer complex was polymerized in water as a solvent in the presence of a free radical redox initiator, yielding a side‐chain polyrotaxane. Two main fractions of the resulting polymeric product were isolated by extraction with water. About 50 wt.‐% of the polymer material contains approximately 40 mol‐% of noncovalently anchored cyclodextrin with regard to the amount of side‐chain units. This fraction is not soluble in water. Additionally, a smaller water‐soluble fraction with a significantly lower degree of polymerization was isolated bearing nearly one cyclodextrin on each side‐chain unit.