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Guest‐responsive excimer emission in an α‐helix peptide bearing γ‐cyclodextrin and two naphthalene units
Author(s) -
Toyoda Takayuki,
Matsumura Sachiko,
Mihara Hisakazu,
Ueno Akihiko
Publication year - 2000
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/(sici)1521-3927(20000501)21:8<485::aid-marc485>3.0.co;2-o
Subject(s) - excimer , naphthalene , peptide , helix (gastropod) , moiety , cyclodextrin , chemistry , fluorescence , monomer , stereochemistry , crystallography , polymer chemistry , organic chemistry , polymer , biochemistry , ecology , physics , snail , biology , quantum mechanics
An α‐helix peptide (17 amino acids) bearing γ‐cyclodextrin (γ‐CD) and two naphthyl units (γ‐N 2 17) was designed and prepared as a new type of chemosensor. The α‐helix peptide with γ‐CD sandwiched between two naphthyl moieties exhibits excimer emission by inserting the two naphthalene moieties into the γ‐CD cavity from the opposite sides in the side chain of the peptide. The two reference peptides, which have one naphthalene moiety and one γ‐CD unit, exhibit only monomer fluorescence and have larger binding constants for the examined guests than γ‐N 2 17.