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Novel lipase‐catalyzed ring‐opening copolymerization of oxiranes and succinic anhydride forming polyesters bearing functional groups
Author(s) -
Matsumura Shuichi,
Okamoto Takeshi,
Tsukada Keisuke,
Toshima Kazunobu
Publication year - 1998
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/(sici)1521-3927(19980601)19:6<295::aid-marc295>3.0.co;2-0
Subject(s) - succinic anhydride , polyester , lipase , polymer chemistry , copolymer , ether , ring opening polymerization , polymerization , epoxide , yield (engineering) , organic chemistry , chemistry , catalysis , materials science , polymer , enzyme , metallurgy
Oxiranes, such as glycidyl phenyl ether (GPE) and benzyl glycidate (BG), were copolymerized with succinic anhydride (SA) by lipase at a temperature between 60 and 80°C to yield the corresponding polyesters bearing carboxyl or phenyl groups. Bulk polymerization, especially at the temperature of 80°C, and preferably using porcine pancreatic lipase gave biodegradable polyesters with a molecular weight greater than 5000.