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Polymer association in poor solvents: from monomolecular micelles to clusters of chains and phase separation
Author(s) -
Ganazzoli Fabio,
Raos Guido,
Allegra Giuseppe
Publication year - 1999
Publication title -
macromolecular theory and simulations
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.37
H-Index - 56
eISSN - 1521-3919
pISSN - 1022-1344
DOI - 10.1002/(sici)1521-3919(19990101)8:1<65::aid-mats65>3.0.co;2-n
Subject(s) - micelle , macromolecule , folding (dsp implementation) , polymer , chemical physics , chain (unit) , copolymer , globular protein , cluster (spacecraft) , phase (matter) , chemistry , polymer science , crystallography , computer science , physics , organic chemistry , biochemistry , programming language , astronomy , aqueous solution , electrical engineering , engineering
We report some recent results obtained in our laboratory on the poor‐solvent behavior of macromolecules. We first discuss the globular collapse of short chains that, unlike long ones, may form compact ordered states. We then address the collapse of random AB copolymers, which may provide significant clues to understanding biophysical issues such as the protein folding problem or the DNA arrangement in a living cell. Afterwards, we turn to the many‐chain problem of homopolymer aggregation into polymolecular micelles or clusters of chains and eventually phase separation. The unifying feature of our approach consists in the self‐consistent free‐energy minimization with inclusion of intra‐ and inter‐molecular interactions, whenever they are required, that enables us to describe the chain conformation in detail.