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A Convenient and General Tin‐Free Procedure for Radical Conjugate Addition
Author(s) -
Ollivier Cyril,
Renaud Philippe
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(20000303)39:5<925::aid-anie925>3.0.co;2-m
Subject(s) - conjugate , chemistry , reagent , tin , pyridine , environmentally friendly , carbonate , combinatorial chemistry , organic chemistry , mathematical analysis , mathematics , ecology , biology
An environmentally friendly one‐pot reaction for conjugate radical additions to activated olefins, with good to excellent yields, uses organoboranes generated in situ as radical precursors and the Barton carbonate PTOC‐OMe as a radical‐chain transfer reagent [Eq. (1)]. PTOC=pyridine‐2‐thione‐ N ‐oxycarbonyl.