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Bridged Cyclic Oligoribonucleotides as Model Compounds for Codon – Anticodon Pairing
Author(s) -
Micura Ronald,
Pils Werner,
Grubmayr Karl
Publication year - 2000
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/(sici)1521-3773(20000303)39:5<922::aid-anie922>3.0.co;2-y
Subject(s) - pairing , transfer rna , base pair , chemistry , rna , genetic code , stereochemistry , crystallography , biochemistry , physics , dna , gene , superconductivity , quantum mechanics
Only three base pairs make up bridged cyclic RNA double helices (see diagram) which are stable enough for determination of their pairing properties with standard UV and CD spectroscopic methods. These compounds represent new models for the pairing between codon and anticodon.